49ers vs. Cowboys
The Dallas Cowboys host the San Francisco 49ers on Sunday, November 15 at 4:25 PM ET at AT&T Stadium. The 49ers are 4.5-point favorites and the total is 54.5. OPTIMAL's fair odds give the 49ers a 74% chance to win and the Cowboys 26%. This page compares spread, total and moneyline odds across sportsbooks, alternate lines included, alongside the injury report and player props. You can also watch a snap-by-snap simulation of the game.
Simulate GameInjury report
San Francisco 49ers
- Brandon AiyukWROUT
- Christian KirkWRIR
- De'Zhaun StriblingWRIR
- Deebo Samuel Sr.WROUT
- Isaac GuerendoRBOUT
- Jake TongesTEIR
- Mike EvansWROUT
- Ricky PearsallWRIR
- Patrick Taylor Jr.RBQ
Dallas Cowboys
- KaVontae TurpinWROUT
- Malik DavisRBIR
- Princeton FantTEIR
- George PickensWRQ
- Jake FergusonTEQ
- Luke SchoonmakerTEQ
Player props
Open a player for lines, projections and game logsSan Francisco 49ers
No props posted yet
Dallas Cowboys
No props posted yet
Spread odds
As of 4:00 PM ET| Sportsbook | SF -4.5 | DAL +4.5 |
|---|---|---|
| Best price | +100bet365 | -120bet365 |
 Novig |
-104 | – |
 bet365 |
+100 | -120 |
 betPARX |
-113SF -4 | -108DAL +4 |
Total odds
As of 4:00 PM ET| Sportsbook | Over 54.5 | Under 54.5 |
|---|---|---|
| Best price | -108betPARX | +100Novig |
| Novig |
-115 | +100 |
| bet365 |
-114 | -106 |
| betPARX |
-108 | -113 |
Moneyline odds
As of 4:00 PM ET| Sportsbook | SF | DAL |
|---|---|---|
| Best price | -200bet365 | +213Novig |
| Novig |
-1150 | +213 |
 Kalshi |
-322 | +208 |
| bet365 |
-200 | +165 |
 Coinbase |
-322 | +208 |
| betPARX |
-215 | +175 |
American odds. Green is the best price at the selected line; a book without that line shows its closest one under its odds. Lines move until kickoff.
49ers vs. Cowboys questions
What is the 49ers vs. Cowboys prediction?
OPTIMAL's fair odds give the 49ers a 74% chance to win and the Cowboys 26%. That's the moneyline with the sportsbooks' margin taken out: a probability, not a promise.
What is the spread for 49ers vs. Cowboys?
The 49ers are 4.5-point favorites over the Cowboys: 49ers -4.5, Cowboys +4.5, the line the most sportsbooks are pricing. The best price on 49ers -4.5 is +100 at bet365 and on Cowboys +4.5 is -120 at bet365.
What is the over/under for 49ers vs. Cowboys?
The total is 54.5, the line the most sportsbooks are pricing. The best price on the over is -108 at betPARX and on the under is +100 at Novig.
Who is favored in 49ers vs. Cowboys?
The 49ers are the moneyline favorites at -322, with the Cowboys at +208. The best moneyline on the 49ers is -200 at bet365 and on the Cowboys is +213 at Novig.
When is 49ers vs. Cowboys?
The San Francisco 49ers at Dallas Cowboys game is on Sunday, November 15 at 4:25 PM ET, at AT&T Stadium.
Who is injured for 49ers vs. Cowboys?
49ers: Brandon Aiyuk (out), Christian Kirk (injured reserve), De'Zhaun Stribling (injured reserve), Deebo Samuel Sr. (out), Isaac Guerendo (out), Jake Tonges (injured reserve), Mike Evans (out), Ricky Pearsall (injured reserve) and 1 more. Cowboys: KaVontae Turpin (out), Malik Davis (injured reserve), Princeton Fant (injured reserve), George Pickens (questionable), Jake Ferguson (questionable), Luke Schoonmaker (questionable).