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Baltimore Orioles vs. Boston Red Sox: Preview, Predictions and Picks for May 25, 2025

Updated on:
May 25, 2025 2:38 PM
The Boston Red Sox, riding a 2-1 series advantage, aim to secure a series victory over the Orioles at Fenway Park on Sunday. The Red Sox, sitting at 27-27, will look to capitalize on their 16-13 home record against the Orioles, who have struggled on the road with a 9-19 record. First pitch is set for 1:35 PM on Sunday.
Baltimore Orioles vs Boston Red Sox

Current Odds

BAL
BOS
Over
5.5
+125
Under
4.5
+120
BAL
-3.5
+177
BOS
+1.5
+285
BAL
ML
-810
BOS
ML
+700

Orioles vs Red Sox statistics

Stat Orioles Red Sox
Hits 400 (24th) 476 (2nd)
Batting Average .235 (22nd) .254 (8th)
Runs Batted In 185 (25th) 255 (6th)
Runs 195 (25th) 266 (5th)
Home Runs 56 (Tied-11th) 69 (7th)
Walks 148 (25th) 182 (11th)
Stolen Bases 30 (23rd) 51 (Tied-6th)
Strikeouts 460 (25th) 484 (28th)
Pitches 7568 (16th) 8137 (1st)

Boston Red Sox recent games

Game Date Opponent Result Score
5/24/25 vs Baltimore Orioles L 2-1
5/24/25 vs Baltimore Orioles W 6-5 F/10
5/23/25 vs Baltimore Orioles W 19-5
5/21/25 vs New York Mets L 5-1
5/20/25 vs New York Mets W 2-0

Baltimore Orioles recent games

Game Date Opponent Result Score
5/24/25 @ Boston Red Sox W 2-1
5/24/25 @ Boston Red Sox L 6-5 F/10
5/23/25 @ Boston Red Sox L 19-5
5/21/25 @ Milwaukee Brewers W 8-4 F/11
5/20/25 @ Milwaukee Brewers L 5-2

Boston Red Sox injuries

  • Seby Zavala (C): Day-To-Day
  • Romy Gonzalez (1B): 10-Day-IL
  • Zach Penrod (RP): 60-Day-IL
  • Chris Murphy (RP): 60-Day-IL
  • Jovani Moran (RP): Day-To-Day

Baltimore Orioles injuries

  • Brandon Young (P): Day-To-Day
  • Carlos Tavera (RP): Day-To-Day
  • Tyler O'Neill (RF): 10-Day-IL
  • Gary Sanchez (C): 10-Day-IL
  • Cody Poteet (RP): 15-Day-IL

Orioles vs Red Sox game info

Type Info
Venue Fenway Park
Location Boston, Massachusetts
First pitch Sun 1:35 PM
Temperature 59°
Chance of Rain 16%

Orioles vs Red Sox predictions

When you look at the Baltimore Orioles lineup heading into Game 4 against the Boston Red Sox, a few names stand out as potential difference-makers. Ryan O’Hearn has been seeing the ball well lately, and I’d expect him to continue getting on base with solid contact—something around a hit or so per game feels likely. Cedric Mullins has developed a knack for delivering in big moments, so don’t be surprised if he leaves the yard or knocks in a couple runs, playing his usual aggressive style on the bases. Gunnar Henderson should also find a way to contribute, possibly working some good at-bats and adding to the Orioles’ hit column. Dean Kremer, taking the mound, has had his ups and downs, but if he can limit hard contact and keep the walks in check for at least five solid innings, Baltimore could keep things tight.

On the flip side at Fenway, the Boston Red Sox enter this matchup with their bats trending in the right direction. Rafael Devers is always a threat to go deep, and with the way he’s been swinging, I won’t be shocked if he launches one, racks up a couple of RBIs, or both. Jarren Duran brings a dynamic spark at the top of the order—he’s got a shot to get on base multiple times, maybe swipe a bag, and set the table for the heart of the lineup. Wilyer Abreu, too, looks like someone who could grab an extra-base hit or two, especially facing a righty in Kremer. On the mound, Walker Buehler’s command will be crucial, and if he attacks the strike zone, I’d pencil him in for five-plus innings with a handful of strikeouts, helping to keep Boston right in the thick of things.

At the end of the day, with the Red Sox holding a 2-1 series lead and their offense firing on all cylinders, it’s tough to bet against them at Fenway. The lineup has just been so deep lately, and with guys like Devers leading the charge, Boston looks primed to close out this series strong. The Orioles might make it interesting, especially if the top half of their order gets cooking, but I see the Red Sox holding serve at home and taking this one. What do you think—will Boston’s bats be too much for Baltimore, or do the O’s have a surprise in store? Either way, it’s shaping up to be a fun one.

Boston Red Sox

Baltimore Orioles

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