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Seattle Mariners vs. Houston Astros: Preview, Predictions and Picks for May 25, 2025

Updated on:
May 25, 2025 3:41 PM
The Houston Astros, holding a 2-1 advantage, face off against the Seattle Mariners at Daikin Park on Sunday, May 25, 2025, at 2:10 PM. The Astros look to capitalize on their 17-10 home record, while the Mariners aim to leverage their 16-11 road record to even the series. The AL West rivals are neck and neck, making for an intense matchup in this pivotal Game 4.
Seattle Mariners vs Houston Astros

Current Odds

SEA
HOU
Over
7.5
-122
Under
8.5
-120
SEA
-1.5
+360
HOU
+1.5
-132
SEA
ML
+201
HOU
ML
+129

Mariners vs Astros statistics

Stat Mariners Astros
Hits 407 (21st) 434 (Tied-11th)
Batting Average .236 (21st) .251 (11th)
Runs Batted In 227 (10th) 198 (Tied-19th)
Runs 235 (10th) 209 (Tied-18th)
Home Runs 70 (6th) 48 (20th)
Walks 205 (2nd) 157 (21st)
Stolen Bases 49 (9th) 24 (28th)
Strikeouts 459 (24th) 397 (7th)
Pitches 7886 (5th) 7286 (26th)

Houston Astros recent games

Game Date Opponent Result Score
5/24/25 vs Seattle Mariners W 2-1
5/23/25 vs Seattle Mariners L 5-3
5/22/25 vs Seattle Mariners W 9-2
5/21/25 @ Tampa Bay Rays L 8-4
5/20/25 @ Tampa Bay Rays L 3-2

Seattle Mariners recent games

Game Date Opponent Result Score
5/24/25 @ Houston Astros L 2-1
5/23/25 @ Houston Astros W 5-3
5/22/25 @ Houston Astros L 9-2
5/21/25 @ Chicago White Sox W 6-5
5/20/25 @ Chicago White Sox L 1-0

Houston Astros injuries

  • Brice Matthews (SS): Day-To-Day
  • Ray Gaither (SP): Day-To-Day
  • Yordan Alvarez (LF): 10-Day-IL
  • Jose Fleury (SP): Day-To-Day
  • Pedro Leon (RF): 10-Day-IL

Seattle Mariners injuries

  • Taylor Dollard (SP): Day-To-Day
  • Bryce Miller (SP): 15-Day-IL
  • Trent Thornton (RP): 15-Day-IL
  • Cade Marlowe (LF): Day-To-Day
  • Jackson Kowar (RP): 60-Day-IL

Mariners vs Astros game info

Type Info
Venue Daikin Park
Location Houston, Texas
First pitch Sun 2:10 PM
Temperature 92°
Chance of Rain 1%

Mariners vs Astros predictions

Seattle fans are pretty pumped for what’s shaping up to be a big night at Daikin Park, especially with Luis Castillo taking the mound for the Mariners. When Castillo pitches, you can almost pencil in five strong innings and a handful of strikeouts—he’s the kind of guy who brings reliable energy game after game. At the plate, look for Cal Raleigh to keep flexing his power swing; I wouldn’t be shocked if he goes deep again, especially since he’s been the heart of this lineup. J.P. Crawford is another name to keep an eye on—he’s been surprisingly steady with the bat and should give Houston’s starter some problems with his patient approach and knack for getting on base. And if you’re hoping for a little chaos on the basepaths, keep tabs on Julio Rodriguez, who has both speed and a hot bat right now.

On the other side, the Houston Astros are sending out Colton Gordon, and that’s going to be a tough challenge for Seattle’s hitters. Gordon tends to keep things close, and he’s been steadily racking up strikeouts, so expect a few shut-down innings early on. Jake Meyers has been absolutely raking and could easily turn the tide with a multi-hit game; he’s showing no signs of slowing down with his batting average. Meanwhile, Isaac Paredes is always a threat for a clutch homer or key RBI—he’s that guy who seems to show up whenever it matters most. Plus, you can’t ever count out Jose Altuve to quietly rack up hits and score runs; he’s the definition of consistency and sets an electric tone at the top of the lineup.

So, who’s taking this one? The Mariners have a slight edge from their recent momentum, but Houston’s bats are looking dangerous—especially with Paredes and Meyers dialed in. Still, with Castillo anchoring the rotation and Seattle’s lineup getting timely contributions from up and down the order, I’ve got to lean slightly toward the Mariners squeaking out a tight win at home. It might come down to a big swing late or an extra-base hit when it matters most. Looks like we’re in for a really close one, so get ready for some late-inning drama!

Houston Astros

Seattle Mariners

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