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Arizona Diamondbacks vs. Los Angeles Dodgers: Preview, Predictions and Picks for May 21, 2025

Updated on:
May 21, 2025 9:07 PM
The Los Angeles Dodgers, sitting atop the NL West with a 30-19 record, welcome the fourth-place Arizona Diamondbacks, who are 26-23 overall, to Dodger Stadium on Wednesday at 10:10 PM. The series is currently tied 3-3, and the Dodgers will look to capitalize on their strong 18-8 home record has been a key factor in their success.
Arizona Diamondbacks vs Los Angeles Dodgers

Current Odds

ARI
LAD
Over
9.5
+108
Under
9.5
-112
ARI
+1.0
-110
LAD
-1.5
+150
ARI
ML
+143
LAD
ML
-143

Diamondbacks vs Dodgers statistics

Stat Diamondbacks Dodgers
Hits 423 (Tied-7th) 449 (1st)
Batting Average .255 (8th) .268 (1st)
Runs Batted In 248 (5th) 270 (2nd)
Runs 255 (5th) 281 (2nd)
Home Runs 69 (Tied-3rd) 80 (2nd)
Walks 190 (2nd) 187 (4th)
Stolen Bases 44 (9th) 34 (Tied-18th)
Strikeouts 369 (6th) 400 (16th)
Pitches 7416 (4th) 7550 (2nd)

Los Angeles Dodgers recent games

Game Date Opponent Result Score
5/20/25 vs Arizona Diamondbacks W 4-3 F/10
5/19/25 vs Arizona Diamondbacks L 9-5
5/18/25 vs Los Angeles Angels L 6-4
5/17/25 vs Los Angeles Angels L 11-9
5/16/25 vs Los Angeles Angels L 6-2

Arizona Diamondbacks recent games

Game Date Opponent Result Score
5/20/25 @ Los Angeles Dodgers L 4-3 F/10
5/19/25 @ Los Angeles Dodgers W 9-5
5/18/25 vs Colorado Rockies W 1-0
5/17/25 vs Colorado Rockies L 14-12
5/16/25 vs Colorado Rockies W 8-0

Los Angeles Dodgers injuries

  • Edgardo Henriquez (SP): 60-Day-IL
  • Michael Kopech (RP): 60-Day-IL
  • Roki Sasaki (SP): 15-Day-IL
  • Giovanny Gallegos (RP): Day-To-Day
  • Kirby Yates (RP): 15-Day-IL

Arizona Diamondbacks injuries

  • Justin Martinez (RP): 15-Day-IL
  • Eduardo Rodriguez (SP): 15-Day-IL
  • A.J. Puk (RP): 60-Day-IL
  • Jordan Montgomery (SP): 60-Day-IL
  • Blake Walston (SP): 60-Day-IL

Diamondbacks vs Dodgers game info

Type Info
Venue Dodger Stadium
Location Los Angeles, California
First pitch Wed 10:10 PM
Temperature 79°
Chance of Rain 0%

Diamondbacks vs Dodgers predictions

When you look at the Arizona Diamondbacks, there’s no question that their lineup features some real threats heading into this matchup. I’d keep an eye on Corbin Carroll, who’s shaping up to have a strong game—he’s likely to swipe a base and drive in a run, maybe even send one out of the park given his power numbers this season. Geraldo Perdomo has been one of the most consistent bats in their lineup, and it looks like he’ll be setting the table again with a couple of hits and a chance to cross the plate at least once. You can’t forget about Eugenio Suarez either; he’s been locked in with runners in scoring position and could add to his already impressive RBI total.

Switching over to the Los Angeles Dodgers, it’s the heart of this order that really stands out. Freddie Freeman just doesn’t stop hitting—expect him to rack up at least one, probably two hits, and contribute with a run scored. Shohei Ohtani is always the wild card; with the way he’s swinging the bat lately, a home run definitely feels within reach, and his ability to steal a base or draw a walk keeps pitchers off balance. Teoscar Hernandez adds a little more punch to the lineup, and I wouldn’t be surprised if he delivers an extra-base hit and drives in a run. Then there’s their ace on the mound, Dustin May, who should be able to contain Arizona’s lineup over five or six solid innings with a handful of strikeouts.

When you put it all together, it feels like the Dodgers have the edge coming in—especially at home, where they’ve been tough to beat. Their bats are just relentless, and with Dustin May on the hill, they seem poised to control the tempo from the first pitch. While the Diamondbacks have enough talent to keep things interesting, I’m leaning toward the Los Angeles Dodgers to take this one and break the series tie. What do you think—will the boys in blue come out on top again, or does Arizona have a surprise in store?

Los Angeles Dodgers

Arizona Diamondbacks

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