Up arrow
MLB
Games

Baltimore Orioles vs. Milwaukee Brewers: Preview, Predictions and Picks for May 21, 2025

Updated on:
May 21, 2025 2:09 PM
The Baltimore Orioles, looking to snap an 8-game losing streak, travel to American Family Field on Wednesday at 1:10 PM to take on the Milwaukee Brewers, who lead the series 2-0. The Orioles, struggling with a 7-17 road record, will aim to get back on track against their 15-9 home record. Can the Orioles finally get their season back on track with a much-needed win?
Baltimore Orioles vs Milwaukee Brewers

Current Odds

BAL
MIL
Over
5.5
+156
Under
4.5
+135
BAL
-1.5
+453
MIL
-1.5
+227
BAL
ML
+400
MIL
ML
-476

Orioles vs Brewers statistics

Stat Orioles Brewers
Hits 357 (25th) 370 (23rd)
Batting Average .230 (25th) .230 (24th)
Runs Batted In 166 (25th) 188 (Tied-16th)
Runs 175 (25th) 208 (14th)
Home Runs 55 (10th) 40 (Tied-26th)
Walks 132 (Tied-26th) 169 (Tied-10th)
Stolen Bases 26 (Tied-23rd) 63 (Tied-1st)
Strikeouts 420 (24th) 399 (15th)
Pitches 6882 (21st) 7126 (14th)

Milwaukee Brewers recent games

Game Date Opponent Result Score
5/20/25 vs Baltimore Orioles W 5-2
5/19/25 vs Baltimore Orioles W 5-4
5/18/25 vs Minnesota Twins W 5-2
5/17/25 vs Minnesota Twins L 7-0
5/16/25 vs Minnesota Twins L 3-0

Baltimore Orioles recent games

Game Date Opponent Result Score
5/20/25 @ Milwaukee Brewers L 5-2
5/19/25 @ Milwaukee Brewers L 5-4
5/18/25 vs Washington Nationals L 10-4
5/17/25 vs Washington Nationals L 10-6
5/16/25 vs Washington Nationals L 4-3

Milwaukee Brewers injuries

  • Aaron Civale (SP): 15-Day-IL
  • Aaron Ashby (RP): 15-Day-IL
  • DL Hall (SP): 60-Day-IL
  • Jose Quintana (SP): 15-Day-IL
  • Garrett Mitchell (CF): 10-Day-IL

Baltimore Orioles injuries

  • Andrew Kittredge (RP): 15-Day-IL
  • Carlos Tavera (RP): Day-To-Day
  • Ramon Laureano (LF): Day-To-Day
  • Robinson Martinez (RP): Day-To-Day
  • Brandon Young (P): Day-To-Day

Orioles vs Brewers game info

Type Info
Venue American Family Field
Location Milwaukee, Wisconsin
First pitch Wed 1:10 PM
Temperature 46°
Chance of Rain 68%

Orioles vs Brewers predictions

If you’re an Orioles fan, you’re probably feeling the weight of that eight-game skid, and you’re hoping the bats wake up at American Family Field. But there are glimmers for optimism on Baltimore’s side. Cedric Mullins seems primed to shake things up, possibly launching another homer and driving in key runs—he’s got that sneaky speed and power combo that always keeps pitchers on their toes. Keep an eye out for Ryan O’Hearn and Adley Rutschman, too; both are hot with the bat lately and could string together some timely hits to ignite the offense. And with Tomoyuki Sugano taking the mound, there’s a fair shot he’ll keep it competitive if he can eat up a few quality innings and limit the damage early.

Switching gears over to the Milwaukee Brewers, there’s an obvious sense of confidence, especially playing at home where they’ve looked strong. William Contreras looks set for a solid showing behind the plate and at bat, likely picking up a couple of hits and controlling the game defensively. Christian Yelich always feels like a threat to go deep or run wild on the bases, making him a potential game-changer in any close scenario. Then there’s Rhys Hoskins, steady as ever, who could be the difference if the Brewers need a key RBI in a late-inning spot. Starter Chad Patrick should be able to put together decent innings, racking up a handful of strikeouts and giving Milwaukee a good foundation to build on.

So, how is this matchup likely to unfold? The Orioles are definitely due for a breakout, and there’s talent in that lineup to pull off a surprise—baseball rarely follows the script. But with the Milwaukee Brewers holding the home edge, showing greater depth on offense, and having more momentum at their back, it just feels like the odds tilt towards the Brew Crew notching another win. Of course, anything can happen, but if you’re asking who’s more likely to walk off the field smiling, Milwaukee looks like the safer bet right now.

Milwaukee Brewers

Baltimore Orioles

More Games