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San Francisco Giants vs. Detroit Tigers: Preview, Predictions and Picks for May 28, 2025

Updated on:
May 28, 2025 2:33 PM
The Detroit Tigers aim to extend their impressive 20-8 record at Comerica Park as they host the San Francisco Giants on Wednesday, May 28, at 1:10 PM. The Tigers are looking to keep their two-game series lead alive against the Giants, who are 14-15 on the road this season. With a strong 36-20 overall and 20-8 home record, Detroit is poised to continue their dominance at home.
San Francisco Giants vs Detroit Tigers

Current Odds

SF
DET
Over
7.5
+130
Under
7.5
+116
SF
+1.5
-157
DET
-1.5
+360
SF
ML
+800
DET
ML
-400

Giants vs Tigers statistics

Stat Giants Tigers
Hits 417 (Tied-24th) 478 (Tied-7th)
Batting Average .230 (24th) .253 (11th)
Runs Batted In 228 (12th) 271 (Tied-4th)
Runs 239 (Tied-12th) 284 (4th)
Home Runs 54 (17th) 65 (9th)
Walks 191 (12th) 188 (13th)
Stolen Bases 26 (27th) 20 (30th)
Strikeouts 465 (21st) 494 (26th)
Pitches 8108 (14th) 8259 (5th)

Detroit Tigers recent games

Game Date Opponent Result Score
5/27/25 vs San Francisco Giants W 3-1
5/26/25 vs San Francisco Giants W 3-1
5/25/25 vs Cleveland Guardians W 5-0
5/24/25 vs Cleveland Guardians L 7-5 F/10
5/23/25 vs Cleveland Guardians L 3-1

San Francisco Giants recent games

Game Date Opponent Result Score
5/27/25 @ Detroit Tigers L 3-1
5/26/25 @ Detroit Tigers L 3-1
5/25/25 @ Washington Nationals W 3-2
5/24/25 @ Washington Nationals L 3-0
5/23/25 @ Washington Nationals W 4-0

Detroit Tigers injuries

  • Dietrich Enns (RP): Day-To-Day
  • Reese Olson (SP): 15-Day-IL
  • Parker Meadows (CF): 60-Day-IL
  • Wilmer Flores (SP): Day-To-Day
  • Matt Vierling (CF): 10-Day-IL

San Francisco Giants injuries

  • Cole Waites (RP): Day-To-Day
  • Ethan Small (SP): Day-To-Day
  • Ryan Murphy (SP): Day-To-Day
  • Jerar Encarnacion (RF): 60-Day-IL
  • Justin Verlander (SP): 15-Day-IL

Giants vs Tigers game info

Type Info
Venue Comerica Park
Location Detroit, Michigan
First pitch Wed 1:10 PM
Temperature 58°
Chance of Rain 58%

Giants vs Tigers predictions

Looking at the San Francisco Giants lineup, there are a few players who could stand out against the Tigers’ pitching. Jung Hoo Lee has been the table-setter for the Giants with an impressive .281 batting average, so you can expect him to keep making solid contact—maybe picking up a hit or two and putting pressure on Detroit’s defense. Wilmer Flores, always a threat in the middle of the order, seems primed for a productive game—don’t be shocked to see him drive in a run and possibly go deep if Jackson Jobe hangs one over the plate. Keep an eye on Matt Chapman and Mike Yastrzemski, too; either one is fully capable of sneaking an extra-base hit or even a homer, given the right matchup.

When you shift focus to the Detroit Tigers, you can see why Comerica Park has become such a tough place for visiting teams. Riley Greene consistently finds ways to spark the offense and should be good for at least a hit while working the count and picking up a walk. Spencer Torkelson brings serious power into every series, so I wouldn’t be surprised if he launches a big fly or tacks on an RBI or two. Kerry Carpenter and Dillon Dingler round out a lineup that can string together hits; both are likely to have a multi-hit night if the Tigers get into the Giants’ bullpen early. On the pitching side, Jackson Jobe looks dialed in—he should deliver a strong outing with a handful of strikeouts and keep San Francisco chasing.

With Detroit holding down a 20-8 home record and the momentum of a winning streak, they feel like the team to back in this matchup. The Tigers’ combination of top-10 hitting, power up and down the lineup, and a hot hand on the mound gives them a clear edge. San Francisco’s got some pop and will make things interesting, but with the Tigers finding ways to win in front of their home crowd, I’m leaning toward Detroit extending their streak and making it another tough night for the Giants. What do you think—can the Giants break through, or are the Tigers just too tough at Comerica right now?

Detroit Tigers

San Francisco Giants

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