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Cleveland Guardians vs. Athletics: Preview, Predictions and Picks for June 22, 2025

Updated on:
Jun 22, 2025 5:25 PM
The Cleveland Guardians, currently sitting second in the AL Central with a 38-37 record, take on the Athletics, who are struggling in fifth place in the AL West with a 32-47 record, at Sutter Health Park on Sunday, June 22, 2025, at 4:05 PM. The series is tied 1-1, setting the stage for a crucial rubber match. The Guardians will look to capitalize on their 19-22 road record, while the Athletics aim to turn their fortunes around at home, where they're 15-26 on the season.
Cleveland Guardians vs Athletics

Current Odds

CLE
ATH
Over
3.5
+340
Under
4.0
-159
CLE
-3.5
+521
ATH
+2.5
+335
CLE
ML
-1000
ATH
ML
+1400

Guardians vs Athletics statistics

Stat Guardians Athletics
Hits 562 (29th) 681 (2nd)
Batting Average .230 (25th) .252 (10th)
Runs Batted In 268 (25th) 324 (13th)
Runs 283 (25th) 335 (13th)
Home Runs 75 (22nd) 98 (7th)
Walks 230 (21st) 253 (15th)
Stolen Bases 60 (13th) 43 (Tied-21st)
Strikeouts 616 (12th) 655 (20th)
Pitches 10755 (27th) 11211 (17th)

Athletics recent games

Game Date Opponent Result Score
6/21/25 vs Cleveland Guardians L 4-2
6/20/25 vs Cleveland Guardians W 5-1
6/19/25 vs Houston Astros W 6-4 F/10
6/18/25 vs Houston Astros L 11-4
6/17/25 vs Houston Astros L 13-3

Cleveland Guardians recent games

Game Date Opponent Result Score
6/21/25 @ Athletics W 4-2
6/20/25 @ Athletics L 5-1
6/19/25 @ San Francisco Giants L 2-1
6/18/25 @ San Francisco Giants W 4-2
6/17/25 @ San Francisco Giants W 3-2

Athletics injuries

  • Zack Gelof (2B): 60-Day-IL
  • Brady Basso (RP): 60-Day-IL
  • Miguel Andujar (LF): 10-Day-IL
  • Shea Langeliers (C): 10-Day-IL
  • Ken Waldichuk (SP): 60-Day-IL

Cleveland Guardians injuries

  • Erik Sabrowski (RP): 60-Day-IL
  • Paul Sewald (RP): 15-Day-IL
  • Trevor Stephan (RP): 60-Day-IL
  • Shane Bieber (SP): 60-Day-IL
  • John Means (SP): 60-Day-IL

Guardians vs Athletics game info

Type Info
Venue Sutter Health Park
Location Sacramento, California
First pitch Sun 4:05 PM

Guardians vs Athletics predictions

If you’re watching the Cleveland Guardians this season, you know certain guys seem ready to rise to the occasion. Jose Ramirez, always the table-setter, looks set to drive the offense again with his consistent bat—don’t be shocked if he racks up a couple of hits and maybe sends one deep. Carlos Santana might not be leading in raw power anymore, but his ability to get on base and bring runners home makes him dangerous in the clutch. And keep an eye on Steven Kwan at the top of the order; his knack for getting on base and putting pressure on the defense could very well ignite some rallies. Slade Cecconi, taking the mound for the Guardians, has the kind of approach that could keep the A’s in check, especially if he settles into a rhythm early.

Switching over to the Athletics, their offense is led by the ever-steady Jacob Wilson, who just keeps finding ways to slap base hits and set things up for the bigger bats behind him. Brent Rooker is the kind of guy who can change a game with one swing—he’s got the power to punish mistakes, and with Sutter Health Park’s dimensions, you can’t rule out a long ball. Tyler Soderstrom is another name to watch, especially if he gets any ducks on the pond—he’s proved plenty capable of bringing the runs home. On the hill, JP Sears gives Oakland a real shot to keep things close, especially if he attacks Guardians hitters and avoids free passes. There’s also something about Lawrence Butler’s energy that gives this lineup a spark, so don’t be surprised if he causes some headaches on the bases.

When it comes down to a prediction, this looks like one of those tight matchups where the little things make all the difference. The Guardians have been edging out close games lately, and their combination of contact bats and solid pitching gives them an edge. Oakland’s bats could absolutely make some noise, especially if Rooker or Soderstrom get going early, but with Cecconi on the mound and Ramirez locked in at the plate, I’m leaning toward Cleveland eking out a tough win in this latest chapter of their series. What are you expecting—will the Guardians hold strong, or can the A’s pull off the upset at home?

Sacramento Athletics

Cleveland Guardians

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