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St. Louis Cardinals vs. San Diego Padres: Preview, Predictions and Picks for August 2, 2025

Updated on:
Aug 2, 2025 11:31 AM
The San Diego Padres, riding a three-game home win streak, welcome the St. Louis Cardinals to Petco Park on Saturday, August 2nd at 10:10 PM. With a 35-18 home record, the Padres look to extend their lead in the NL West, while the Cardinals aim to bounce back from a 23-32 road record. This crucial matchup marks the second game of the series, with the Padres leading 1-0.
St. Louis Cardinals vs San Diego Padres

Current Odds

STL
SD
Over
8.5
-113
Under
8.5
+103
STL
+1.5
-162
SD
-1.5
+150
STL
ML
+136
SD
ML
-137

Cardinals vs Padres statistics

Stat Cardinals Padres
Hits 928 (Tied-13th) 918 (Tied-16th)
Batting Average .249 (14th) .250 (12th)
Runs Batted In 462 (Tied-15th) 420 (25th)
Runs 484 (14th) 449 (24th)
Home Runs 106 (23rd) 92 (29th)
Walks 346 (Tied-18th) 346 (Tied-18th)
Stolen Bases 62 (Tied-21st) 74 (17th)
Strikeouts 846 (4th) 771 (3rd)
Pitches 16134 (14th) 15642 (25th)

San Diego Padres recent games

Game Date Opponent Result Score
8/1/25 vs St. Louis Cardinals W 4-1
7/30/25 vs New York Mets W 5-0
7/29/25 vs New York Mets W 7-1
7/28/25 vs New York Mets W 7-6
7/27/25 @ St. Louis Cardinals W 9-2

St. Louis Cardinals recent games

Game Date Opponent Result Score
8/1/25 @ San Diego Padres L 4-1
7/30/25 vs Miami Marlins L 2-0
7/29/25 vs Miami Marlins L 5-0
7/28/25 vs Miami Marlins W 7-1
7/27/25 vs San Diego Padres L 9-2

San Diego Padres injuries

  • Nestor Cortes (SP): 60-Day-IL
  • Michael King (SP): 60-Day-IL
  • Ethan Salas (C): Day-To-Day
  • Joe Musgrove (SP): 60-Day-IL
  • Jhony Brito (RP): 60-Day-IL

St. Louis Cardinals injuries

  • Lars Nootbaar (LF): 10-Day-IL
  • Drew Rom (SP): Day-To-Day
  • Nolan Arenado (3B): 10-Day-IL
  • John King (RP): 15-Day-IL
  • Zack Thompson (RP): 60-Day-IL

Cardinals vs Padres game info

Type Info
Venue Petco Park
Location San Diego, California
First pitch Sat 10:10 PM
Temperature 70°
Chance of Rain 0%

Cardinals vs Padres predictions

All eyes are on the St. Louis Cardinals as they take the field at Petco Park. I’m particularly interested to see how Alec Burleson swings the bat—he’s been consistent lately and I wouldn’t be surprised to see him tally a hit or two and maybe drive in a run. Willson Contreras has shown some pop this season, so watch out for him to get on base and possibly go deep, adding to his team-leading home run total. Plus, Brendan Donovan’s ability to spray hits all over the field means he could be a spark plug near the top of the lineup. With Michael McGreevy on the mound, the Cardinals are hoping he can keep the Padres’ bats quiet through at least five strong innings and limit the damage on the scoreboard.

On the San Diego Padres’ side, Manny Machado continues to be the man. He’s got the hot hand and should put together another multi-hit game—and let’s face it, when Machado is locked in, the rest of the lineup seems to follow his lead. Fernando Tatis is another guy to watch; with his speed and power, he’s always a threat to ignite a rally or pop a ball into the seats. And don’t overlook Luis Arraez and Jackson Merrill, both of whom have a knack for getting on base and setting the table for the big hitters. On the hill, Randy Vasquez looks poised to give the Padres some quality innings and put his team in a strong position early.

With the Padres rolling on a three-game home win streak and looking super comfortable at Petco Park, it’s tough to bet against them in this matchup. The lineup has been firing on all cylinders, and the combination of solid starting pitching with the offensive firepower of guys like Machado and Tatis should give them an edge. The Cardinals have their moments, but the way the Padres have been playing at home lately, I think they’ll keep that streak alive and grab another win against St. Louis. What do you think—can the Padres keep the momentum going?

San Diego Padres

St. Louis Cardinals

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