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San Francisco Giants vs. Chicago Cubs: Preview, Predictions and Picks for May 6, 2025

Updated on:
May 7, 2025 2:07 AM
The San Francisco Giants look to snap their four-game road skid as they face the Chicago Cubs at Wrigley Field on Tuesday, May 6, 2025, at 7:40 PM. The Giants, tied with the Cubs at 22-14 mark, will need to capitalize on their 10-9 road record to even the series, which currently favors the Cubs 1-0.
San Francisco Giants vs Chicago Cubs

Current Odds

SF
CHC
Over
7.0
-104
Under
6.5
+117
SF
+1.0
-125
CHC
-1.5
+170
SF
ML
+131
CHC
ML
-136

Giants vs Cubs statistics

Stat Giants Cubs
Hits 273 (22nd) 332 (1st)
Batting Average .231 (24th) .262 (1st)
Runs Batted In 157 (11th) 213 (1st)
Runs 166 (12th) 217 (1st)
Home Runs 38 (Tied-13th) 54 (3rd)
Walks 126 (12th) 140 (3rd)
Stolen Bases 22 (Tied-21st) 46 (1st)
Strikeouts 308 (25th) 288 (Tied-18th)
Pitches 5285 (10th) 5611 (1st)

Chicago Cubs recent games

Game Date Opponent Result Score
5/5/25 vs San Francisco Giants W 9-2
5/4/25 @ Milwaukee Brewers L 4-0
5/3/25 @ Milwaukee Brewers W 6-2
5/2/25 @ Milwaukee Brewers W 10-0
5/1/25 @ Pittsburgh Pirates W 8-3

San Francisco Giants recent games

Game Date Opponent Result Score
5/5/25 @ Chicago Cubs L 9-2
5/4/25 vs Colorado Rockies W 9-3
5/3/25 vs Colorado Rockies W 6-3
5/2/25 vs Colorado Rockies W 4-0
5/1/25 vs Colorado Rockies L 4-3

Chicago Cubs injuries

  • Tyson Miller (RP): 15-Day-IL
  • Ryan Brasier (RP): 15-Day-IL
  • Eli Morgan (RP): 15-Day-IL
  • Shota Imanaga (SP): 15-Day-IL
  • Brandon Birdsell (RP): Day-To-Day

San Francisco Giants injuries

  • Ethan Small (SP): Day-To-Day
  • Cole Waites (RP): Day-To-Day
  • Enny Romero (RP): Out
  • Tyler Fitzgerald (2B): 10-Day-IL
  • Joel Peguero (SP): Day-To-Day

Giants vs Cubs game info

Type Info
Venue Wrigley Field
Location Chicago, Illinois
First pitch Tue 7:40 PM
Temperature 67°
Chance of Rain 0%

Giants vs Cubs predictions

When the San Francisco Giants take the field against the Chicago Cubs, key players to watch include Jung Hoo Lee and Justin Verlander, both of whom could be game-changers. Lee, with his impressive batting average, is likely to get on base at least once or twice today. His consistent performance is a source of optimism for the Giants as they look to curb their four-game road skid. Verlander, the experienced pitcher, will be aiming to keep the Cubs' heavy hitters in check. If Verlander can put together a solid performance, giving up minimal runs and maintaining his strikeout prowess, it could tilt the game's momentum in the Giants' favor. Will Wilmer Flores, with his home run power, be the extra spark the Giants need today? The possibility is enticing.

Turning to the Chicago Cubs, they've got their own arsenal of talent ready to step up, with Ian Happ and Kyle Tucker possibly leading the charge. Happ’s ability to consistently rack up hits and Tucker’s knack for finding the fences are essential against the Giants. Adding to that, Seiya Suzuki's driving in of runs has the crowd at Wrigley Field excited about what he might contribute to the scoreline. With Colin Rea on the mound, striking out the way he knows how, the Cubs' pitching could offer the kind of resistance needed to stifle the Giants' bats. His performance might just be the tipping point Cubs fans are banking on to secure another home victory.

When it comes to picking a winner, it’s hard to deny that both teams are evenly matched with identical records, making this clash even more thrilling. Considering the Cubs’ strong hitting statistics and their knack for scoring runs, they might have the slight upper hand, especially with the advantage of playing in front of their home crowd. But don't count the Giants out just yet, especially if Verlander finds his rhythm on the mound. However, given the Cubs' recent form and home field consistency, they seem well-positioned to edge past the Giants in this one. Of course, that's just one point of view – the beauty of baseball is you never really know until that final out. What do you think? Will this one be as close as it seems on paper?

Chicago Cubs

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