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Houston Astros vs. Los Angeles Angels: Preview, Predictions and Picks for June 21, 2025

Updated on:
Jun 21, 2025 2:22 PM
The Houston Astros, riding a 1-0 series lead, take on the Los Angeles Angels at Angel Stadium on Saturday, June 21st at 9:38 PM. The Astros, sitting atop the AL West with a 44-32 record, will look to build on their momentum against the fourth-place Angels, who are struggling with a 36-39 record.
Houston Astros vs Los Angeles Angels

Current Odds

HOU
LAA
Over
8.0
-108
Under
8.5
-105
HOU
+1.0
-138
LAA
-1.5
+177
HOU
ML
+116
LAA
ML
-118

Astros vs Angels statistics

Stat Astros Angels
Hits 658 (Tied-6th) 559 (28th)
Batting Average .258 (2nd) .224 (29th)
Runs Batted In 309 (Tied-15th) 294 (21st)
Runs 324 (15th) 305 (22nd)
Home Runs 81 (Tied-14th) 107 (4th)
Walks 221 (23rd) 189 (29th)
Stolen Bases 43 (Tied-21st) 35 (Tied-28th)
Strikeouts 586 (6th) 731 (29th)
Pitches 10636 (26th) 10761 (21st)

Los Angeles Angels recent games

Game Date Opponent Result Score
6/20/25 vs Houston Astros L 3-2 F/10
6/19/25 @ New York Yankees L 7-3
6/18/25 @ New York Yankees W 3-2
6/17/25 @ New York Yankees W 4-0
6/16/25 @ New York Yankees W 1-0 F/11

Houston Astros recent games

Game Date Opponent Result Score
6/20/25 @ Los Angeles Angels W 3-2 F/10
6/19/25 @ Athletics L 6-4 F/10
6/18/25 @ Athletics W 11-4
6/17/25 @ Athletics W 13-3
6/16/25 @ Athletics L 3-1

Los Angeles Angels injuries

  • Kevin Newman (SS): Day-To-Day
  • Victor Gonzalez (RP): Day-To-Day
  • Yoan Moncada (3B): 10-Day-IL
  • Jorge Soler (RF): 10-Day-IL
  • Angel Felipe (RP): Day-To-Day

Houston Astros injuries

  • Taylor Trammell (LF): 10-Day-IL
  • Glenn Otto (RP): Day-To-Day
  • Blake Weiman (RP): Day-To-Day
  • Brendan Rodgers (2B): 10-Day-IL
  • Pedro Leon (RF): 10-Day-IL

Astros vs Angels game info

Type Info
Venue Angel Stadium
Location Anaheim, California
First pitch Sat 9:38 PM
Temperature 64°
Chance of Rain 1%

Astros vs Angels predictions

When you look at the Houston Astros’ lineup heading into Game 2 against the Los Angeles Angels, it’s hard not to expect another strong showing from key bats. Jeremy Pena is carrying a hot .328 average and has looked locked in lately, so don’t be surprised if he racks up multi-hit night here, maybe even crossing the plate once or twice. Isaac Paredes, who leads the club in both home runs and RBIs, is another guy who can make noise—he’s got both the patience and the pop to send a ball deep or push runners across. Sprinkle in contributions from contact guys like Jose Altuve and Yainer Diaz, both projected for a hit or more each, and the Astros’ top half looks ready to do damage against Jose Soriano. On the mound, Brandon Walter should be good for solid innings, with an expected handful of strikeouts and a knack for keeping the ball in the park.

On the flip side, the Angels’ lineup has some pop too, but they’ve had to scratch and claw for offense all season. Taylor Ward is always a threat—leading the team with 19 homers and 50 RBIs—but I see him settling in for a single hit and maybe driving in a run if the top of the order gets aboard. Nolan Schanuel can spray the ball around and should be good for a hit, as well, while Luis Rengifo’s ability to reach base and swipe a bag or two could be a wild card if he can get on. It’s Logan O’Hoppe I’d keep an eye on behind the plate—he’s coming off a couple of clutch performances and looks primed to sneak in an extra-base hit. Starter Jose Soriano has shown flashes of brilliance but expect the Astros to work his pitch count and scratch out a couple of runs through the middle innings.

All things considered, the Houston Astros just seem to have too much firepower and depth up and down the lineup for the Los Angeles Angels. Houston comes in with confidence and a lineup that’s been consistently putting the ball in play, while the Angels are still figuring out how to find rhythm against top pitching. Combine that with Walter’s steady hand on the mound and the Astros’ opportunistic offense, and it feels like Houston is in a great spot to take Game 2 and stretch their series lead. Are you leaning the same way? This one shapes up as another notch in the win column for the ‘Stros.

Los Angeles Angels

Houston Astros

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