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San Francisco Giants vs. Chicago White Sox: Preview, Predictions and Picks for June 28, 2025

Updated on:
Jun 28, 2025 4:58 PM
The San Francisco Giants, currently sitting second in the NL West with a 45-37 record, look to build on their series lead as they take on the struggling Chicago White Sox, who own a 26-56 record, at Guaranteed Rate Field on Saturday, June 28 at 4:10 PM. The Giants will aim to capitalize on the White Sox's poor home record of 17-24.
San Francisco Giants vs Chicago White Sox

Current Odds

SF
CHW
Over
2.5
-120
Under
2.5
+116
SF
-1.5
+618
CHW
-1.5
+300
SF
ML
+351
CHW
ML
-350

Giants vs White Sox statistics

Stat Giants White Sox
Hits 622 (26th) 590 (30th)
Batting Average .232 (24th) .220 (30th)
Runs Batted In 328 (Tied-19th) 267 (28th)
Runs 347 (Tied-17th) 281 (28th)
Home Runs 79 (Tied-22nd) 64 (28th)
Walks 296 (3rd) 269 (14th)
Stolen Bases 43 (Tied-24th) 56 (Tied-18th)
Strikeouts 685 (Tied-17th) 713 (21st)
Pitches 12080 (12th) 11761 (20th)

Chicago White Sox recent games

Game Date Opponent Result Score
6/27/25 vs San Francisco Giants L 3-1
6/25/25 vs Arizona Diamondbacks W 7-3
6/24/25 vs Arizona Diamondbacks L 4-1
6/23/25 vs Arizona Diamondbacks L 10-0
6/22/25 @ Toronto Blue Jays W 4-2

San Francisco Giants recent games

Game Date Opponent Result Score
6/27/25 @ Chicago White Sox W 3-1
6/26/25 vs Miami Marlins L 12-5
6/25/25 vs Miami Marlins L 8-5 F/10
6/24/25 vs Miami Marlins L 4-2
6/22/25 vs Boston Red Sox W 9-5

Chicago White Sox injuries

  • Luis Robert Jr. (CF): Day-To-Day
  • Jared Shuster (RP): 15-Day-IL
  • Jesse Scholtens (RP): 60-Day-IL
  • Edgar Navarro (RP): Day-To-Day
  • Davis Martin (SP): 15-Day-IL

San Francisco Giants injuries

  • Jerar Encarnacion (RF): 10-Day-IL
  • Ryan Murphy (SP): Day-To-Day
  • Casey Schmitt (3B): Day-To-Day
  • Ethan Small (SP): Day-To-Day
  • Matt Chapman (3B): 10-Day-IL

Giants vs White Sox game info

Type Info
Venue Rate Field
Location Chicago, Illinois
First pitch Sat 4:10 PM
Temperature 81°
Chance of Rain 0%

Giants vs White Sox predictions

Looking ahead at this Giants vs. White Sox matchup, a few San Francisco bats and arms really stand out with serious potential to swing things in favor of the visitors. Heliot Ramos, who has been a reliable spark plug in the lineup, looks primed to keep the hits coming—don’t be surprised if you see him notch another 1 or 2 tonight, maybe even send one over the fence given his recent home run pace. Wilmer Flores is also trending well, and with his knack for clutch RBIs, it’s easy to picture him driving in at least one run, especially with runners on the corners. On the bump, Robbie Ray is expected to have a strong outing, likely giving up only a couple runs over five-plus innings while racking up a solid total of strikeouts, which should help keep the Giants steady through the middle frames.

Switching over to the home team, the Chicago White Sox are searching for someone to step up and halt the Giants’ momentum. Don’t underestimate Miguel Vargas—his pop at the plate can change the dynamic in a hurry, and he’s a good bet to connect for at least one extra-base hit and maybe a run scored. Luis Robert brings that power-speed combo everybody talks about, making him a real threat to get on base and put pressure on the defense. Adrian Houser is likely to put in a gritty start on the mound, but keeping the Giants’ lineup in check for longer than five innings could prove to be a tall order.

So which side gets the upper hand at Rate Field? It just feels like the Giants have a little more firepower and consistency, especially with their lineup’s patience and ability to manufacture runs. If Robbie Ray holds steady and the bats do their thing, San Francisco has a strong shot at taking this one and stretching their series lead. The White Sox may put up a fight, especially with a few dangerous bats lurking, but the edge tilts toward the Giants in this showdown. How do you see it playing out?

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