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Kansas City Chiefs vs. Arizona Cardinals: Preview, Predictions and Picks for August 9, 2025

Updated on:
Aug 5, 2025 7:07 PM
The Kansas City Chiefs are set to face off against the Arizona Cardinals on Saturday, August 9, 2025, at 8:00 PM at State Farm Stadium. Both teams look to kick off their season on a high note, with the Chiefs seeking to capitalize on their road game momentum and the Cardinals aiming to defend their home turf. This early-season matchup promises to be an exciting contest between two hungry teams.
Kansas City Chiefs vs Arizona Cardinals

Current Odds

KC
ARI
Over
38.5
-107
Under
38.5
-110
KC
+1.0
-105
ARI
-1.5
-105
KC
ML
+110
ARI
ML
-120

Arizona Cardinals recent games

Game Date Opponent Result Score
1/5/25 vs San Francisco 49ers W 47-24
12/28/24 @ Los Angeles Rams L 13-9
12/22/24 @ Carolina Panthers L 36-30 OT
12/15/24 vs New England Patriots W 30-17
12/8/24 vs Seattle Seahawks L 30-18

Kansas City Chiefs recent games

Game Date Opponent Result Score
2/9/25 vs Philadelphia Eagles L 40-22
1/26/25 vs Buffalo Bills W 32-29
1/18/25 vs Houston Texans W 23-14
1/5/25 @ Denver Broncos L 38-0
12/25/24 @ Pittsburgh Steelers W 29-10

Arizona Cardinals injuries

  • Valentin Senn (OT): Injured Reserve
  • Joey Blount (S): Questionable
  • BJ Ojulari (LB): Out
  • Quez Watkins (WR): Injured Reserve
  • Marvin Harrison Jr. (WR): Questionable

Kansas City Chiefs injuries

  • Eric Scott Jr. (CB): Injured Reserve
  • Darius Rush (CB): Injured Reserve
  • Deon Bush (S): Questionable
  • Jared Wiley (TE): Questionable
  • Kristian Fulton (CB): Out

Chiefs vs Cardinals game info

Type Info
Venue State Farm Stadium
Location Glendale, AZ
Kickoff Sat 8:00 PM
Temperature 108°
Chance of Rain 0%

Chiefs vs Cardinals predictions

Let’s talk Chiefs, because whenever Kansas City takes the field, the spotlight usually finds Patrick Mahomes. You can almost count on him spreading the ball around, but keep an eye on Travis Kelce—he’s Mahomes’ go-to when things get tight. Don’t be surprised if Kelce racks up a handful of catches and finds the end zone at least once. As for the ground game, Isiah Pacheco should get his share of carries and might even break off a few chunk plays, especially against a Cardinals defense that has had some trouble containing running backs in the past. With that much firepower, KC’s offense could get rolling early.

Flipping over to the desert, the Cardinals are hoping Kyler Murray is ready to make some noise. If he’s looking sharp, his ability to escape pressure and make plays with his legs could really stress that Chiefs defensive front. On the outside, look for Marquise “Hollywood” Brown to be the main beneficiary of Murray’s attention—if the two connect early, it could open things up for everyone else. And don’t count out James Conner; if Arizona’s offense wants to keep pace, pounding the rock and keeping Mahomes off the field will be key.

So when it comes down to picking a winner, the odds are tilting toward Kansas City for a reason. The Chiefs just seem to have more weapons on offense and a knack for finding a way to win, especially when games get close late. Still, with this being Arizona’s home opener at State Farm Stadium, the energy will be high, and you can bet Murray will try to keep things interesting. In the end, though, I’d back Mahomes and company to come out on top, probably covering that narrow spread. Wouldn’t shock me if it’s a shootout, but the Chiefs feel like the safer pick here.

Arizona Cardinals

No
Arizona Cardinals
players

Kansas City Chiefs

No
Kansas City Chiefs
players

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